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AZD9291Z中间体1421372-66-8现货特价供应
2018-01-06


Certificate of Analysis



COMMERCIAL NAME:

Osimertinib intermediate 4



PRODUCT NAME:

N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-



1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine


CHEMICAL FORMULA:

C25H31N7O





CAS No. :

1421372-66-8












Batch No.


Date of

Date of


Date of

Package


Manufacture

Expiry


Analysis












170501


06/05/2017

05/05/2019


09/05/2017

1kg/pack








Items



Specifications


Results





Appearance


White to tinted (gray, purple gray, beige, etc.) Solid

Conforms





Identification


HPLC: The retention time of the major peak in the

Conforms


chromatogram conforms to the characteristic peak of R.S.










Water



Not more than 1.0%


0.61%







Related Substances


Any other impurity: Not more than 0.5%

0.39%


Total impurities: Not more than 2.0%

0.42%










Assay



97.0%~102.0%



99.1%

(on the anhydrous basis)

















Conclusion



Qualified